CHICAGO (AP) — Carlos Rodon felt good coming out of the bullpen before the game. It was all downhill from there.

Rodon was knocked out in the first inning, and the Chicago White Sox managed just three hits in a 7-0 loss to the Los Angeles Angels on Monday night.

"Wasn't really missing when I was down in the 'pen and then it didn't translate over when I got in the game," Rodon said. "Just didn't happen."

Kole Calhoun, Andrelton Simmons and Geovany Soto hit consecutive RBI singles during a five-run first, matching the Angels' season high for runs in an entire game. Mike Trout scored on a throwing error by first baseman Jose Abreu, and Johnny Giavotella capped the opening outburst with another RBI single.

Rodon (1-2) got only one out before he was replaced by Jake Petricka. The No. 3 pick in the 2014 amateur draft allowed six hits and walked two in the shortest of his 29 major league appearances.

"He wasn't locating. He was all over the place," Chicago manager Robin Ventura said. "It just looked like (catcher Dioner Navarro) was having to get him back in line and they also put it in play. They hit him pretty good, too. Not a good night for 'Los, and we didn't swing it that well, either."

Angels left-hander Hector Santiago matched a career high with 10 strikeouts over seven crisp innings in his second career start against his former team. Santiago (1-0), traded to Los Angeles in a three-team deal in 2013 that moved Adam Eaton to Chicago, yielded two hits and walked three.

"Coming back here, it's definitely fun facing my old team, no doubt," Santiago said. "It was fun tonight. Last year I faced them that first time and they got me, and we're even now."

The White Sox opened a seven-game homestand with their third consecutive loss after an 8-2 start to the season. Jimmy Rollins doubled and walked twice, but Jose Abreu and Eaton had the only other hits for slumping Chicago.

Greg Mahle worked the eighth and Mike Morin finished the three-hitter for Los Angeles' first shutout of the season. The White Sox have scored 11 runs in their last six games.

"We need to get this offense going," Eaton said. "Again, there's a ton of talent. We all know that. I think that's the reason we've come up with a question mark is because we know this offense can produce and it will."

Simmons and C.J. Cron each had three hits as the Angels rebounded from a weekend sweep by the Twins. Simmons extended his hitting streak to 11 games, equaling a career high, and Cron busted out of a 4-for-40 start to the season after he was pushed down to eighth in the lineup.

"I didn't think too much into it. I'm still in the lineup, I can't complain," Cron said. "As long as you're in the lineup you want to help the team win, and that's kind of my mindset, no matter how rough the start's been."

ROSTER MOVE

The White Sox optioned reserve outfielder J.B. Shuck to Triple-A Charlotte after the game. They plan to call up a pitcher on Tuesday.

"With the way tonight's game went, you need another arm," Ventura said. "I think the bullpen did a great job of coming in and being able to take care of the innings to get through it."

TRAINER'S ROOM

Angels LHP Tyler Skaggs, coming back from Tommy John surgery, is scheduled to throw four innings for Triple-A Salt Lake on Wednesday. He had been limited to three innings in each of his first two outings with the Bees.

UP NEXT

White Sox RHP Mat Latos (2-0, 0.75 ERA) and Angels RHP Matt Shoemaker (1-1, 6.00) take the mound for the second game of the series. Latos has allowed one run in 12 innings this season, and Shoemaker pitched six scoreless innings in his previous start at Oakland on Wednesday.

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Jay Cohen can be reached at http://www.twitter.com/jcohenap