ST. LOUIS (AP) _ Mark McGwire hit his 499th career home run, and tied Sammy Sosa for the major league lead with 42 homers this year, in the seventh inning Wednesday night.

McGwire hit a 1-0 pitch from San Diego reliever Carlos Reyes an estimated 436 feet, a drive that cleared the left-field bullpen. The homer lifted the St. Louis Cardinals into a 6-all tie with the Padres.

Earlier in the day, Sosa homered for the Cubs against Montreal.

McGwire and Sosa have homered on the same day 35 times the last two seasons, including 15 times this year.

McGwire leads the NL with 99 RBIs, including 11 in the last six games. He was 2-for-4 with a bases-loaded infield hit in the third, a popup and a strikeout.