LOUISVILLE, Ky. (AP) — Officials say five people including three children have been killed in a head-on crash on a two-lane highway in northern Kentucky.

Independence Fire Chief Scott Breeze said the collision happened Thursday and involved two vehicles. He said the five killed were in one vehicle and a sixth person in the other vehicle was flown to the University of Cincinnati Medical Center.

Kenton County Police Chief Spike Jones says police have determined that a Honda Pilot driven by 54-year-old Daniel Greis crossed the center line and struck a car being driven by 26-year-old Rodney Pollitt Jr. of Independence. Pollitt and his four passengers died at the scene. They included 27-year-old Samantha Malohn, 6-year-old Cailie Pollitt, 8-year-old Brenden Pollitt and 9-year-old Hailieann Pollitt, all of Dry Ridge.

Jones said the cause of the crash remains under investigation.