NEW YORK (AP) — For the first time in the professional era of tennis, a top-seeded woman has lost her opening match at the U.S. Open. Simona Halep was overwhelmed by the power-based game of 44th-ranked Kaia Kanepi of Estonia, who won today's first-round match 6-2, 6-4 in just 76 minutes. Top-seeded women have lost in the first round of major tournaments five times, but never at the U.S. Open.

NEW YORK (AP) — The 2016 U.S. Open men's champion, Stan Wawrinka, has returned to the event with a first-round win over eighth-seeded Grigor Dimitrov. Wawrinka had to miss the event last year after knee surgery.

HOUSTON (AP) — Oakland plays at Houston in the opener of a three-game series between the top two teams in the AL West. Gerrit Cole pitches for the World Series champion Astros, who have won five straight and lead the division by 1½ games. Athletics lefty Brett Anderson is 3-1 with a 2.11 ERA in eight starts since coming off the disabled list.

NEW YORK (AP) — Three years ago, Daniel Murphy powered the Mets into the World Series by going 9 for 17 with four home runs to win NLCS MVP honors in a four-game sweep of the Cubs. Now, he'll face his former team for the first time as a member of the Cubs when they host Noah Syndergaard and the Mets tonight at Wrigley Field. Murphy has tormented New York since leaving town as a free agent, batting .390 with 11 homers in 44 games against the Mets for the Washington Nationals, who traded him to Chicago last week. Jon Lester starts for the Cubs.

SAN ANTONIO (AP) — Manu Ginobili has announced his retirement at age 41, ending a career in which he helped the San Antonio Spurs win four NBA championships in 16 seasons with the club. inobili's pro career lasted 23 seasons in all, starting with stints in Italy and his native Argentina before he came to San Antonio in 2002. He formed what was a "Big 3" with the Spurs, alongside Tim Duncan and Tony Parker.