ROME (AP) _ Police shut the office of a Neapolitan gynecologist charged with secretly impregnating a patient with sperm not from her husband, but from a donor who passed on a hereditary disease.

An indictment issued Tuesday also charges Raffaele Magli with using only two sperm donors to fertilize eggs that resulted in ``hundreds or thousands'' of births, ``in violation of the most basic protocol of bioethics.''

Police shut Magli's office in Naples' fashionable Mergellina neighborhood Tuesday on orders from prosecutor Nicola Ciccarelli, whose indictment called the gynecologist ``a public peril.''

``We're happy above all for the shutting down of his office so others won't suffer the same abuse we did,'' the husband, Roberto Minucci, told RAI state TV.

Magli, 40, apparently is the first doctor indicted for alleged abuse of Italy's highly unregulated but quickly growing field of ``test-tube'' births.

Cristina Iervolino became suspicious of Magli when her daughter Giada, now 2, was diagnosed as having thalassemia, a potentially fatal type of anemia. Both parents must be carriers for a baby to get the disease; Iervolino is a carrier but Minucci is not.

Magli accused Iervolino of conceiving the child in an extra-marital affair. He also has sued the couple, claiming they tried to extort $600,000 in exchange for a promise not to go to the police. The lawsuit is pending.

The indictment accuses Magli of fraud and aggravated personal injury. It contends the doctor recommended artificial insemination for the couple when they could have had children themselves, then used a donor's sperm instead of the husband's without telling the couple.

Magli also is charged with not running checks on the sperm, which apparently carried the hereditary disease. A preliminary hearing was scheduled for Oct. 4.

The indictment accuses Magli of substituting ``himself for nature, without the consent of the patients, deciding paternity as he pleased, using the sperm of only two donors to result in hundreds or thousands of babies born with the same genetic inheritance, in violation of the most basic protocol of bioethics,'' according to the Italian news agency ANSA.

Apparently none of the other women has come forward.

Italy has few rules governing medical work to assist pregnancies, but Italy's professional board of physicians has recently cracked down. The board censured Magli, and on Sunday developed a new code of discipline to cover fertility practices. Violation can bring suspension or a ban on practicing.

The board also is studying the case of a Rome gynecologist who announced the birth of a baby conceived after her mother's death. The baby was conceived with the mother's egg, frozen before she died in a car crash, and the sperm of her husband. The embryo was then implanted in the uterus of the man's sister, who gave birth.