Major business and economic events scheduled for Wednesday.

All times are Eastern.

WASHINGTON — Institute for Supply Management releases its manufacturing index for October, 10 a.m.

WASHINGTON — Commerce Department releases construction spending for September, 10 a.m.

WASHINGTON — Federal Reserve policymakers release a statement on interest rates, 2 p.m.

DETROIT — Automakers release vehicle sales for October.

TOKYO — Honda reports earnings.

Facebook Inc. reports quarterly financial results after the market close.

Tesla Inc. reports quarterly financial results after the market close.