NEWTON, Mass. (AP) _ Relatives of Yelena Bonner on Friday prepared for her long-sought visit, cleaning the cluttered, smoke-filled rooms where her family directed an international campaign for her release from internal exile in the Soviet Union.

Mrs. Bonner, wife of Soviet dissident Andrei Sakharov, was to arrive Saturday evening in this Boston suburb and then to finalize plans for diagnosis and treatment of her heart problems.

She will stay at the white frame house of her 35-year-old daughter, Tatiana Yankelevich, who has directed media coverage of her mother's trip to the West from the living room of her comfortable home on tree-lined Maplewood Avenue since late October.

To obtain permission for the trip, Mrs. Bonner signed an agreement with Soviet authorities not to talk to reporters while she is in the West.

A State Department official in Washington said Friday that in light of that the government won't invite her to the White House.

''We're very mindful of the delicacy of her trip and we don't want to be perceived as encumbering her visit,'' said the official, who would not be identified further. ''If she wants to see someone, we will defer to her wishes.''

On Friday, Mrs. Yankelevich would not talk to reporters and spent the day washing windows, grocery shopping, cleaning the basement and setting up clothing racks and a trundle bed.

''They usually don't pay too much attention to their house, so it's easy to see the change in activity,'' said Judith Frampton, who lives across the street. ''I saw them washing windows, pulling out old carpet and there are all those (furniture) crates out front now.

''It's like anybody's relatives coming that they haven't seen in a long time,'' added Ms. Frampton.

It has been six years since Mrs. Yankelevich saw her mother. Mrs. Bonner, 62, was in internal exile in the Soviet city of Gorky until last week, when the government allowed her to travel to Italy and the United States for medical treatment.

Mrs. Yankelevich's husband, Efrem, who handles Sakharov's affairs, has been in Italy with Mrs. Bonner, along with Mrs. Bonner's son, Alexi Semyonov, 29.

Mrs. Bonner, who saw an eye doctor in Siena for her glaucoma and cataracts, received a visa at the U.S. Embassy in Rome early Friday. She spoke with U.S. Ambassador Maxwell Rabb and accepted a letter of welcome from Secretary of State George P. Shultz.

Mrs. Bonner also met with Italian Premier Bettino Craxi and told reporters the meeting was a tribute to her husband, a physicist who won the Nobel Peace Prize in 1975.

Pope John Paul II also received Mrs. Bonner, but the Vatican gave no details of the meeting. The pope received the Yankeleviches last year.

Efrem Yankelevich has been a full-time crusader for the freedom of Mrs. Bonner and Sakharov, who staged several hunger strikes to win his wife's release.

The Yankeleviches, chain-smoking and sometimes flanked by their young son and daughter, have held countless news conferences in their home, coordinating an international effort to draw attention to the case.

Newton police said they were preparing for the onslaught of reporters expected to follow Mrs. Bonner to this middle-class neighborhood just west of Boston.

''We've been in contact with the family and whatever security needs they have, we'll help them,'' said Lt. James O'Donnell. ''We don't want their tranquility disturbed if they don't.''

Neighbors said they, too, were making preparations.

''Usually, there is no traffic on Maplewood Avenue,'' said Jacquie Parker. ''I better do my shopping today so I can get down the road before the traffic starts.''

Other neighbors said they supported the Yankeleviches' campaign for Mrs. Bonner's freedom, and were keeping a lookout.

''We spend a lot of time looking out the window,'' said Ms. Frampton. ''When we see a car we don't recognize, we wonder maybe they're from the Secret Service or the KGB. We joke about it.''