STANFORD, Calif. (AP) _ Netscape founder Jim Clark gave Stanford University $150 million to help build a cross-disciplinary science center that will seek cures for human diseases, the university said Tuesday.

Clark's is the most valuable gift given to Stanford since the donation by Leland Stanford that founded the university in 1891. Clark was a computer professor at Stanford before going into business for himself.

The new center will attempt to break down barriers between biologists, chemists and other academics to help them develop new ways to do research. It is set to open in 2002.

Clark's gift will pay for a new 225,000-square foot building, known on campus as ``Bio-X,'' to house 400 scientists and technicians. It will also supply equipment, endow faculty positions and fund graduate student fellowships.

Clark taught computing at Stanford from 1979 to 1982, where he developed a computer chip that allowed him to found computer system maker Silicon Graphics.

He went on to found Netscape and medical information systems maker Healtheon. His current project, myCFO.com, provides integrated financial management to rich individuals.

He said the freedom Stanford gave him helped make him rich, and he wanted to return the favor.