DENVER (AP) — Miami Heat guard Dwyane Wade was out of the lineup Friday with injuries to both shoulders.

Coach Erik Spoelstra said one shoulder has a "slight sprain and the other one is a little bit of an impingement issue that he's had."

This is the first game Wade will miss this season due to injury.

Wade had 16 points and eight rebounds in the Heat's 104-90 loss to the Los Angeles Clippers on Wednesday. Spoelstra said the injuries were limiting Wade in the loss. "He fought through it but he really needs some rest and treatment," Spoelstra said.

Wade, in his 13th season, is second on the team in scoring (18.4 points) and assists (4.6) per game.