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BERLIN (AP) _ Belgium teen-ager Justine Henin needed four match points but picked up the biggest win of her career Thursday, stunning Venus Williams 6-1, 6-4 to reach the fourth round of the German Open.

The 18-year-old handed the second-ranked American her first loss since Feb. 17 in Nice, France, a streak of 14 matches, although Williams did pull out of her semifinal match against sister Serena in the midst of that run with an injury.

Williams, coming off two straight titles, made numerous unforced errors until Henin drove a backhand deep into the corner, then easily put away the American's weak return to end the match.

Henin, ranked 18th in the world, won the year's first two tournaments in Australia, putting together a 13-match winning streak in the process.

The loss by Williams spoiled a showdown with top-seeded Martina Hingis, who rolled past France's Nathalie Dechy 6-3, 6-1 to reach the quarterfinals of the $1.185 million event.