SAN FRANCISCO (0-0) at MINNESOTA (0-0)

Sunday, 1 p.m. EDT, Fox

OPENING LINE - Vikings by 5

RECORD VS. SPREAD - San Francisco 9-7, Minnesota 12-4

SERIES RECORD - 49ers lead 23-22-1

LAST MEETING - 49ers beat Vikings 20-3, Sept. 14, 2015

AP PRO32 RANKING - 49ers No. 15, Vikings No. 3

49ERS OFFENSE - OVERALL (12), RUSH (21), PASS (9)

49ERS DEFENSE - OVERALL (24), RUSH (22), PASS (22)

VIKINGS OFFENSE - OVERALL (11), RUSH (7), PASS (11)

VIKINGS DEFENSE - OVERALL (1), RUSH (2), PASS (2)

STREAKS, STATS AND NOTES - Vikings have won five straight games at home vs. 49ers since losing 20-17 on Dec. 13, 1992. ... Kyle Shanahan, starting second season as 49ers head coach, was offensive coordinator for current Vikings QB Kirk Cousins' first two years in NFL with Washington. ... 49ers closed 2017 with five straight wins, coinciding with QB Jimmy Garoppolo's takeover as starter. ... Garoppolo, including two victories for New England, has won all seven career NFL starts. He's one of five QBs since 1970 AFL-NFL merger with streak that long. ... 49ers WR Marquise Goodwin finished third in league last season with average of 17.2 yards per catch. ... RB Jerick McKinnon, who played first four years with Vikings, tore ACL in right knee in practice last week and will miss entire season. Matt Breida, with Alfred Morris backing up, takes over as primary RB. ... CB Richard Sherman makes debut with 49ers, after seven years with Seattle. ... Cousins makes debut with Vikings, sixth QB in six seasons to start opener following Sam Bradford, Shaun Hill, Teddy Bridgewater, Matt Cassel, Christian Ponder. ... Cousins went 25 for 37 for 330 yards and two TDs plus rushing TD to lead Washington to 26-24 win vs. 49ers last year. ... Vikings replacing primary starters at LG and RG from last year, with neck injury for Nick Easton and retirement of Joe Berger. Tom Compton and Mike Remmers are in place, with Rashod Hill taking over at RT for Remmers. ... DT Sheldon Richardson, who played for Seattle last year and signed as free agent, is lone new starter on defense that led league in 2017. ... Fantasy Tip: Vikings RB Dalvin Cook returns from season-ending ACL injury to left knee suffered in Week 4 of rookie year. He had 22 carries for 127 yards in season opener in 2017.

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