SAN DIEGO (AP) _ Tony Gwynn's quest for 3,000 career hits was again slowed Tuesday night when he was lifted for a pinch hitter because of a re-aggravated calf injury in the second inning of the San Diego Padres' game against the Philadelphia Phillies.

Gwynn, who was making his third start since missing 19 games because of a strained left calf, was removed due to tightness in the same calf.

Since his return, Gwynn went 2-for-8 to move within 23 hits of becoming the 22nd player to reach the 3,000 mark. He popped up in the first off Philadelphia's Chad Ogea.

Gwynn was placed on the disabled list on May 22. The Padres were 7-12 in his absence.