BOSTON (AP) — Let's see if Louisville's football team can rebound, too.

The Cardinals are coming off a loss to No. 2 Florida State in which they led 21-0 in the second quarter and held a 3-point lead with less than 4 minutes left in the game. Now they visit Boston College, which won at Virginia Tech last week to qualify for a bowl game.

"We've seen how well we can play," Louisville safety Jermaine Reve said as the Cardinals came to terms with the lost opportunity for an upset. "We've seen how good we can be in one half, and we've seen ourselves not play up to our potential in the second half. It all comes from dedication."

Louisville (6-3, 4-3 Atlantic Coast Conference) had climbed as high as No. 21 in The Associated Press Top 25 before a loss to Virginia in Week 3. A victory over the second-ranked team in the nation and defending NCAA champions could have defined the Cardinals' season.

Instead, they need to beat BC (6-3, 3-2), No. 8 Notre Dame and then Kentucky to record the fifth straight nine-win season under coach Bobby Petrino.

"We put a lot into the Florida State preparation, emotionally and on the practice field, and then going out and playing with great effort," said Petrino, who spent four years at Louisville before leaving for a scandal-plague stint with the Atlanta Falcons and Arkansas Razorbacks. "So you just worry about how you rebound from that."

Here are some other things to look for in Saturday night's game in Chestnut Hill:

MINOR HICCUP: Louisville's defense is sixth in the nation, even after giving up 42 points on a season-worst 574 yards to Florida State. "We've played great defense all year long, probably with the exception of the fourth quarter the other night versus a great quarterback," Petrino said. "I think defensively we've just got to continue to do the things we've been doing."

ON THE GROUND: Boston College QB Tyler Murphy has rushed for 965 yards this season, breaking Doug Flutie's school record and just 97 short of the ACC's single-season record for a quarterback set by Clemson's Woodrow Dantzler in 2001. "It's kind of cool, I guess, to surpass somebody like Doug Flutie, who means so much to this place and has done so much," Murphy said. "I don't think my name will stay No. 1 for much longer, but it is cool and it is fun while I'm on top. So, I can't say I don't enjoy it."

BACK TO ACTION: Cardinals receiver DeVante Parker is the team's No. 2 pass-catcher despite playing in just two games. Parker missed the first seven games with a broken bone in his left foot, then returned with nine receptions for 132 yards against North Carolina State and eight receptions for a career-high 214 yards — the second-most in school history — against the Seminoles. "He's just a great player," Petrino said. "So when we call his number he generally gets open and catches it."

GOING BOWLING: Since Addazio took over a team that went 2-10 in 2012, the Eagles have qualified for back-to-back bowl games. "It's 100 percent different," offensive lineman Bobby Vardaro said. "Going 2-10 really crushes you a little bit, especially because all of us are competitors at the highest level. It takes something out of you."