SAN DIEGO (AP) — Padres right-hander Jordan Lyles is pitching a perfect game through six innings against Colorado.

Lyles struck out eight and threw 62 pitches while retiring his first 18 batters Tuesday. The Rockies have hit only one ball out of the infield.

San Diego had a 4-0 lead.

The 27-year-old Conley replaced Bryan Mitchell in the rotation last week. He pitched five effective innings in a 2-1 loss to St. Louis in his first start of the year Thursday night.

The Padres are the only team in the majors without a no-hitter.