Rainier Therapeutics Announces Upcoming Oral and Poster Presentation on Vofatamab at AACR Bladder Cancer Conference
SAN LEANDRO, Calif.--(BUSINESS WIRE)--May 9, 2019--Rainier Therapeutics, Inc., a privately-held clinical stage drug development company, today announced that an abstract related to its FIERCE-22 trial of the company’s lead therapeutic, vofatamab, has been accepted for an oral and poster presentation at the upcoming 2019 American Association for Cancer Research (AACR) Bladder Cancer; Transforming the Field Special Conference, taking place May 18-21, 2019 in Denver, Colorado.
“This presentation will highlight paired biopsy data from the FIERCE-22 trial of vofatamab in combination with pembrolizumab for the treatment of relapsed metastatic bladder cancer showing vofatamab’s effects on immune cell trafficking,” said Scott Myers, Chairman and CEO of Rainier Therapeutics.
Gene expression profiling in wild type and mutant FGFR3 metastatic urothelial cancer treated with combination therapy with vofatamab and pembrolizumab.
Poster Session B25
5 p.m. to 7:30 p.m., Monday, May 20, 2019
Oral session: Plenary Session 8: Management of Metastatic Disease
10:15 a.m. to Noon, Tuesday, May 21, 2019
Presenter: Woonyoung Choi, M.S., Ph.D., John Hopkins School of Medicine
Vofatamab (formerly B-701) is an antibody specifically targeted against the fibroblast growth factor receptor 3 (FGFR3), a known driver of bladder and potentially other FGFR-driven cancers. Vofatamab is the most advanced targeted antibody specific for FGFR3 known by Rainier Therapeutics to be in clinical development. Vofatamab is currently being evaluated in two clinical trials: FIERCE-21 and FIERCE-22.
FIERCE-22 is a Phase 2 trial evaluating vofatamab in combination with pembrolizumab, an immune checkpoint inhibitor, to determine safety, tolerability and efficacy in the treatment of patients with locally advanced or metastatic bladder cancer, who have progressed following platinum-based chemotherapy and who have not received prior immune checkpoint inhibitor therapy. For additional information on FIERCE-22, please visit www.clinicaltrials.gov (NCT03123055).
About Rainier Therapeutics
Rainier Therapeutics, Inc. is a privately held, clinical stage biotechnology company developing vofatamab, a targeted antibody, for the potential treatment of metastatic bladder cancer. For more information, please visit www.rainierrx.com.
View source version on businesswire.com:https://www.businesswire.com/news/home/20190509005350/en/
CONTACT: Julie Rathbun
KEYWORD: UNITED KINGDOM UNITED STATES EUROPE NORTH AMERICA CALIFORNIA COLORADO IRELAND
INDUSTRY KEYWORD: HEALTH BIOTECHNOLOGY CLINICAL TRIALS ONCOLOGY PHARMACEUTICAL RESEARCH FDA SCIENCE
SOURCE: Rainier Therapeutics, Inc.
Copyright Business Wire 2019.
PUB: 05/09/2019 08:00 AM/DISC: 05/09/2019 08:01 AM