4 — Molla Bjurstedt, 1915-18; Helen Jacobs, 1932-1935; Chris Evert, 1975-78.

3 — Hazel Hotchkiss, 1909-11; Mary K. Browne, 1912-14; Molla Bjurstedt Mallory, 1920-22; Helen Wills, 1923-25, 1927-29; Alice Marble, 1938-40; Pauline Betz, 1942-44; Margaret Osborne duPont, 1948-50; Maureen Connolly, 1951-53; Serena Williams, 2012-14.

2 — Bertha Townsend, 1888-89; Mabel Cahill, 1891-92; Juliette Atkinson, 1897-88; Doris Hart, 1954-55; Althea Gibson, 1957-58; Darlene Hard, 1960-61; Maria Bueno, 1963-64; Margaret Smith Court, 1969-70; Billie Jean King, 1971-72; Martina Navratilova, 1983-84, 1986-87; Steffi Graf, 1988-89, 1995-96; Monica Seles, 1991-92; Venus Williams, 2000-01; Kim Clijsters, 2009-10.

Prior to 1968, the United States National Championships was an amateur event. It became the U.S. Open in 1968 when the tournament was open to professionals.