COLLEGE STATION, Texas (AP) — Quarterback Marcus Mariota passed for 221 yards and two touchdowns and ran for two more scores and No. 2 Oregon survived a slow start in college football Saturday to beat Wyoming 48-14.

Oregon erased a 7-0 deficit with four second-quarter touchdowns to take command as Mariota became the fourth Oregon quarterback to pass for more than 7,000 yards. The Ducks junior completed 19 of 23 passes, two for touchdowns.

Mariota also rushed five times for 71 yards, including touchdown runs of 15 and 19 yards.

In other games, No. 3 Alabama, No. 4 Oklahoma and No.7 Texas A&M got impressive wins, but No. 6 Georgia was upset by No.24 South Carolina.

At Tuscaloosa, Alabama, Blake Sims passed for two touchdowns and rushed for a third in three quarters as Alabama's undisputed starting quarterback in a 52-12 victory over Southern Miss.

Sims was 12-of-17 passing for 168 yards for the Crimson Tide ahead of the team's Southeastern Conference opener against Florida.

Most of Sims' completions went to the nation's leading receiver, Amari Cooper. Cooper had eight catches for 135 yards and a touchdown to tie DJ Hall's school record of five consecutive 100-yard games set in 2006. Kenyan Drake scored three touchdowns and produced 59 yards on nine rushes.

Trevor Knight ran for a score and passed for 308 yards to help Oklahoma defeat Tennessee 34-10 for the Sooners' seventh straight win.

Sterling Shepard caught five passes for 109 yards and Keith Ford caught a touchdown pass and ran for a touchdown for Oklahoma.

Justin Worley passed for 201 yards for Tennessee, but he completed just 21 of 44 passes, was sacked five times, threw two interceptions and lost a fumble.

Dylan Thompson threw for three touchdowns and No. 24 South Carolina's maligned defense stood strong on a fourth-quarter goal line stand to topple No. 6 Georgia 38-35.

The Bulldogs had a first-and-goal on the Gamecocks' 4 when down three points with 5:24 remaining. But Hutson Mason was called for intentional grounding to set Georgia back and the usually reliable Marshall Morgan missed a 28-yard field goal.

Todd Gurley ran for 131 yards and a touchdown, yet the Gamecocks kept the Bulldogs' star from making a bigger impact.

Kenny Hill threw for 300 yards and four touchdowns and Texas A&M overcame a slow start for a win over Rice, 38-10.

The win gives the Aggies a 3-0 record for the first time since 2010.

Texas A&M led by 14 points at halftime, but struggled at times to sustain drives and committed several costly penalties, including one that resulted in a touchdown being called back, in the first half.

They got going after halftime with Hill finding Josh Reynolds on a 20-yard touchdown on the first drive of the third quarter. A 1-yard touchdown run by Tra Carson pushed the lead to 35-10 later in the third.

Hill also had TD passes of 14, 13 and 48 yards and has 1,094 yards passing this season to become the first player in school history to throw for 1,000 yards in the first three games of a season.

Driphus Jackson threw for 212 yards and a touchdown and ran for 84 yards for Rice (0-2).

No.8 Baylor thrashed Buffalo 63-21, Boston College beat No. 9 Southern California 37-31 — the Eagles' first victory over a top 10 team in a decade — and No. 10 LSU posted its second-straight shutout, 31-0 over Louisiana-Monroe in other games involving the top 10.